Acute Myeloid Leukemia, Blog

Acute Myeloid Leukemia Signs and Symptoms

Following are some common signs and symptoms of AML, which may help in early diagnosis if attended appropriately:

  • Unexplained weight loss
  • Loss of appetite
  • Fever and night sweats
  • Fatigue and weakness attributable to anemia, other anemia-related symptoms may include shortness of breath and dizziness
  • Recurrent infections like pneumonia due to low WBC count (leukopenia)
  • Increased bleeding tendency, bruising, frequent or severe nosebleeds, and bleeding gums due to low platelet count (thrombocytopenia)
  • Certain type of AML called acute promyelocytic leukemia (APL) is generally associated with bleeding and clotting problems such as deep vein thrombosis and pulmonary embolism
  • Enlargement of the spleen or liver
  • Swelling, pain, and/or bleeding in gums
  • Spread of AML cells to skin may cause chloromas (local collections of blasts) and leukemia cutis (raised, nonpruritic rash)
  • Spread of AML cells to CNS may cause certain symptoms such as headache, seizures, vomiting, chin numbness, blurred vision, and/or balancing problems
  • Spread of AML cells to thoracic cavity may cause difficulty in breathing

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